User profiles for hamm-alvarez-s
Sarah Hamm-AlvarezProfessor of Ophthalmology, USC Verified email at usc.edu Cited by 6552 |
[HTML][HTML] Intracellular trafficking of nonviral vectors
LK Medina-Kauwe, J Xie, S Hamm-Alvarez - Gene therapy, 2005 - nature.com
Nonviral vectors continue to be attractive alternatives to viruses due to their low toxicity and
immunogenicity, lack of pathogenicity, and ease of pharmacologic production. However, …
immunogenicity, lack of pathogenicity, and ease of pharmacologic production. However, …
Targeting receptor-mediated endocytotic pathways with nanoparticles: rationale and advances
S Xu, BZ Olenyuk, CT Okamoto… - Advanced drug delivery …, 2013 - Elsevier
Targeting of drugs and their carrier systems by using receptor-mediated endocytotic
pathways was in its nascent stages 25years ago. In the intervening years, an explosion of …
pathways was in its nascent stages 25years ago. In the intervening years, an explosion of …
Elastin-like polypeptides: Therapeutic applications for an emerging class of nanomedicines
Elastin-like polypeptides (ELPs) constitute a genetically engineered class of ‘protein polymers’
derived from human tropoelastin. They exhibit a reversible phase separation whereby …
derived from human tropoelastin. They exhibit a reversible phase separation whereby …
Identification of the second chromophore of Escherichia coli and yeast DNA photolyases as 5, 10-methenyltetrahydrofolate.
JL Johnson, S Hamm-Alvarez… - Proceedings of the …, 1988 - National Acad Sciences
Denaturation of DNA photolyase (deoxyribodipyrimidine photolyase, EC 4.1.99.3) from
Escherichia coli with guanidine hydrochloride or acidification to pH 2 released, in addition to FAD…
Escherichia coli with guanidine hydrochloride or acidification to pH 2 released, in addition to FAD…
Mechanisms of alveolar epithelial translocation of a defined population of nanoparticles
NR Yacobi, N Malmstadt, F Fazlollahi… - American journal of …, 2010 - atsjournals.org
To explore mechanisms of nanoparticle interactions with and trafficking across lung alveolar
epithelium, we utilized primary rat alveolar epithelial cell monolayers (RAECMs) and an …
epithelium, we utilized primary rat alveolar epithelial cell monolayers (RAECMs) and an …
Site-specific labeling of enveloped viruses with quantum dots for single virus tracking
This study reports a general method of labeling enveloped viruses with semiconductor
quantum dots (QDs) for use in single virus trafficking studies. Retroviruses, including human …
quantum dots (QDs) for use in single virus trafficking studies. Retroviruses, including human …
A rapamycin-binding protein polymer nanoparticle shows potent therapeutic activity in suppressing autoimmune dacryoadenitis in a mouse model of Sjögren's …
Sjögren's syndrome (SjS) is a chronic autoimmune disease characterized initially by lymphocytic
infiltration and destruction of exocrine glands, followed by systemic organ damage and …
infiltration and destruction of exocrine glands, followed by systemic organ damage and …
Cellular uptake of cyclotide MCoTI-I follows multiple endocytic pathways
J Contreras, AYO Elnagar, SF Hamm-Alvarez… - Journal of controlled …, 2011 - Elsevier
Cyclotides are plant-derived proteins that naturally exhibit various biological activities and
whose unique cyclic structure makes them remarkably stable and resistant to denaturation or …
whose unique cyclic structure makes them remarkably stable and resistant to denaturation or …
Polystyrene nanoparticle trafficking across alveolar epithelium
NR Yacobi, L DeMaio, J Xie, SF Hamm-Alvarez… - … , Biology and Medicine, 2008 - Elsevier
We investigated trafficking of polystyrene nanoparticles (PNPs; 20 and 100 nm; carboxylate,
sulfate, or aldehyde-sulfate modified [negatively charged] and amidine-modified [positively …
sulfate, or aldehyde-sulfate modified [negatively charged] and amidine-modified [positively …
Tear cathepsin S as a candidate biomarker for Sjögren's syndrome
Objective The diagnosis of Sjögren's syndrome (SS) in routine practice is largely a clinical
one and requires a high index of suspicion by the treating physician. This great dependence …
one and requires a high index of suspicion by the treating physician. This great dependence …