Targeting of drugs and their carrier systems by using receptor-mediated endocytotic
pathways was in its nascent stages 25years ago. In the intervening years, an explosion of …

Lasp-1 has been identified as a signaling molecule that is phosphorylated upon elevation of
[cAMP]i in pancreas, intestine and gastric mucosa and is selectively expressed in cells …

PATIAL asymmetry is fundamental to the structure and function ofmost eukaryotic cells. A basic
aspect of this polarity is that the cell's plasma membrane is divided into discrete domains. …

Aim: Secretion of proteins into basal tears of Parkinson’s disease (PD) patients may be
altered by changes in nerve function. Materials & methods: Oligomeric α-Syn Oligo and total α-…

The proton‐coupled intestinal dipeptide transporter, PepT1, has 707 amino acids, 12 putative
transmembrane domains (TMD), and is of importance in the transport of nutritional di‐ and …

Vesicular coat proteins mediate the formation of nascent vesicles and select the cargo to be
incorporated therein. As additional coat proteins are discovered that regulate vesicular traffic …

Aim: Due to active engagement of sensory and afferent nerve fibers in reflex tearing which
could be affected in Parkinson's disease (PD), we tested reflex tears as a source of potential …

Gastric HCl secretion by the parietal cell involves the secretagogue‐regulated re‐cycling of
the H + –K + ‐ATPase at the apical membrane. The trafficking of the H + –K + ‐ATPase and …

Molecular events defining enamel matrix removal during amelogenesis are poorly
understood. Early reports have suggested that adaptor proteins (AP) participate in ameloblast‐…

The enamel matrix protein amelogenin is secreted by ameloblasts into the extracellular
space to guide the formation of highly ordered hydroxyapatite mineral crystallites, and, …